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It is best to take a loading dose of 140mg/Kg of your body weight, and afterwards 70mg/Kg every four hours for seventeen hours. So in case you weigh 80Kg, you should take an Original dose of 11,200mg accompanied by 5600mg every four hours for 17 overall hours.Codeine is often a prodrug metabolized by cytochrome P450 2D6 to morphine which mediates m